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Graft-Versus-Host Disease (GvHD)
How is graft-versus-host disease diagnosed?
Diagnosis of GvHD involves:
- Clinical assessment of symptoms
- Biopsies of affected tissues, particularly skin, liver, or intestines
- Blood tests to assess liver and kidney function and other indicators of organ damage
How is graft-versus-host disease treated?
Treatment for GvHD may include:
Corticosteroids: Often the first line of treatment, especially for acute GvHD
Immunosuppressive medications: To reduce the activity of the immune cells causing the disease
Targeted therapies: These include JAK2 inhibitors to treat specific symptoms or manifestations of the disease
Supportive care: Including nutritional support, management of symptoms, and prevention of secondary infections
Management of GvHD is complex and requires a multidisciplinary approach to address both the disease and its complications effectively. Early diagnosis and tailored treatment strategies are critical for improving outcomes and quality of life for affected individuals.
This page has been reviewed by our medical content reviewers.
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